Jacinta O'Shea

DPhil, MSc, MA, BA

Principal Investigator

Associate Researcher, University College
Research Fellow, Donders Institute
Head of Brain Stimulation, FMRIB

Manipulating brain plasticity for therapeutic gain

I am a cognitive neuroscientist interested in the sensorimotor bases of higher cognition (attention, memory, learning). In our group we use neural interference methods, combined with neuroimaging and detailed cognitive and behavioural probes, to make reverse inference about how information processing is organised in the healthy brain. We aim to leverage these insights within an experimental medicine framework to develop novel therapeutics to aid individuals affected by psychiatric or neurological conditions. For more information see our research group website.

Google scholar link: https://scholar.google.co.uk/citations?hl=en&user=BD8dNTUAAAAJ

Key publications

Effect of Prefrontal Cortex Stimulation on Regulation of Amygdala Response to Threat in Individuals With Trait Anxiety: A Randomized Clinical Trial.
Journal article

Ironside M. et al, (2018), JAMA Psychiatry
Induced sensorimotor cortex plasticity remediates chronic treatment-resistant visual neglect.
Journal article

O'Shea J. et al, (2017), Elife, 6
Predicting behavioural response to TDCS in chronic motor stroke.
Journal article

O'Shea J. et al, (2014), Neuroimage, 85 Pt 3, 924 - 933
Contributions of the cerebellum and the motor cortex to acquisition and retention of motor memories.
Journal article

Herzfeld DJ. et al, (2014), Neuroimage, 98, 147 - 158
Individual differences in white-matter microstructure reflect variation in functional connectivity during choice.
Journal article

Boorman ED. et al, (2007), Curr Biol, 17, 1426 - 1431
Functionally specific reorganization in human premotor cortex.
Journal article

O'Shea J. et al, (2007), Neuron, 54, 479 - 490

Recent publications

Precision non-implantable neuromodulation therapies: a perspective for the depressed brain.
Journal article

Borrione L. et al, (2020), Braz J Psychiatry
Inducing Affective Learning Biases with Cognitive Training and Prefrontal tDCS: A Proof-of-Concept Study
Journal article

Overman MJ. et al, (2020), Cognitive Therapy and Research
Methodology for tDCS integration with fMRI.
Journal article

Esmaeilpour Z. et al, (2019), Hum Brain Mapp
3rd European Conference on brain stimulation in psychiatry - From mechanism to medicine.
Journal article

Brunelin J. et al, (2019), Encephale, 45 Suppl 2, S47 - S49
Neural basis of induced phantom limb pain relief.
Journal article

Kikkert S. et al, (2019), Ann Neurol, 85, 59 - 73

More publications