Sean Smart

Senior Research Associate

I am a preclinical imaging scientist specialised in the development of technologies for improving image quality. Key developments include real-time, dynamic reacquistion of motion corrupted data, cardiac synchronisation during short and constant TR steady-state maintained scanning, respiration-gated B₀ stabilisation for high resolution imaging, and the development of a suite of techniques that enable MRI-guided radiotherapy abdomincal tumour to be operated at high throughput.

Recent publications

Protocol for tissue processing and paraffin embedding of mouse brains following ex vivo MRI.

Smart A. et al, (2023), STAR Protoc, 4

A simple, open and extensible gating Control unit for cardiac and respiratory synchronisation control in small animal MRI and demonstration of its robust performance in steady-state maintained CINE-MRI.

Gilchrist S. et al, (2021), Magn Reson Imaging, 81, 1 - 9

Tumour irradiation combined with vascular-targeted photodynamic therapy enhances antitumour effects in pre-clinical prostate cancer.

Sjoberg HT. et al, (2021), Br J Cancer, 125, 534 - 546

Ultrasound-Mediated Gemcitabine Delivery Reduces the Normal-Tissue Toxicity of Chemoradiation Therapy in a Muscle-Invasive Bladder Cancer Model.

Ruan J-L. et al, (2021), Int J Radiat Oncol Biol Phys, 109, 1472 - 1482

MR and CT compatible electrical heating system for mouse imaging

Gilchrist S. et al, (2019), Animal Technology and Welfare, 18, 219 - 221

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