Clemence Ligneul
Research Associate in Preclinical Neuroimaging
I am a postdoctoral research associate from the Preclinical Imaging Group, and an invited member of the WIN Physics Group.
I am interested in the microstructural properties of the developing brain. I am currently focusing on the morphological complexification of cerebellar cells during early postnatal development. To achieve this, I use diffusion-weighted MR spectroscopy (DW-MRS), a method that relies on the diffusion of different intracellular brain metabolites. This project was awarded by a WIN seed grant.
I achieved my PhD at MIRCen (CEA, France, 2014-2017), under the direction of Julien Valette, and explored the rodent brain intracellular space by developing diverse DW-MRS methods. We notably showed that the diffusion properties of myo-inositol reflected the astrocytic morphology.
From 2017 to 2019, I worked at the Champalimaud Foundation (Lisbon, Portugal), where I developed functional MR spectroscopy in the mouse upon visual stimulation.