Research groups
Websites
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Wellcome Centre for Integrative Neuroimaging
Centre
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Nuffield Department of Clinical Neurosciences
Department
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Oxford Sparks
My 'meet the scientist' profile
Stuart Clare
PhD
Associate Professor and Director of Operations, WIN
The last twenty years have seen a huge leap forward in our understanding of how the human brain works, and forefront in the technologies that have enabled this is the technique of functional Magnetic Resonance Imaging (fMRI). My research program involves pushing the technological boundaries of the MRI technique to reveal new insights about how the brain functions normally, and how it is affected by disease.
In 2011 the FMRIB Centre installed a state-of-the-art MRI scanner operating at a magnetic field strength of 7 Tesla. This is over 5 times stronger than a standard clinical system and enables the structure and function of the brain to be studied in far higher detail than has previously been possible.
As well as facilitating clinical and neuroscience research on the Centre's MRI scanners, and leading the Centre's core team, I have a research interest in improving the quality of MRI images using a technique called 'dynamic shimming'.
I am heavily involved in communicating the research we do to the general public (for example, see the animation on the left) and have been working with schools to inspire the next generation of scientists.
Key publications
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Shim optimization with region of interest-specific Tikhonov regularization: Application to second-order slice-wise shimming of the brain.
Shi Y. et al, (2021), Magn Reson Med
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Template-based field map prediction for rapid whole brain B0 shimming.
Shi Y. et al, (2018), Magn Reson Med, 80, 171 - 180
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Feasibility of Diffusion Tensor and Morphologic Imaging of Peripheral Nerves at Ultra-High Field Strength.
Schmid AB. et al, (2018), Invest Radiol, 53, 705 - 713
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Delineating extrastriate visual area MT(V5) using cortical myeloarchitecture.
Bridge H. et al, (2014), Neuroimage, 93 Pt 2, 231 - 236
Recent publications
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Quantitative susceptibility mapping at 7 T in COVID-19: brainstem effects and outcome associations.
Rua C. et al, (2024), Brain
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Why every lab needs a handbook.
Tendler BC. et al, (2023), Elife, 12
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Factors predicting the transition from acute to persistent pain in people with 'sciatica': the FORECAST longitudinal prognostic factor cohort study protocol.
Schmid AB. et al, (2023), BMJ Open, 13
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Subthalamic nucleus shows opposite functional connectivity pattern in Huntington's and Parkinson's disease.
Evangelisti S. et al, (2023), Brain Commun, 5
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Shim optimization with region of interest-specific Tikhonov regularization: Application to second-order slice-wise shimming of the brain.
Shi Y. et al, (2021), Magn Reson Med