Brainwave viscosity in propofol anaesthesia
Fabus MS., Woolrich MW., Warnaby CE.
Human EEG during propofol anaesthesia shows large-scale changes including traveling slow waves1. Slow-wave saturation is a potentially individualised marker of loss of perception2. However, much remains unclear about the dynamics of slow waves. Iterated empirical mode decomposition (itEMD3) is a novel data-driven method for segregating data into physiologically relevant oscillatory modes. We used itEMD to identify spectral modes and their sources / sinks in propofol EEG. Viscosity is a physical quantity expressing the magnitude of resistance to flow. Considering traveling electric potentials in the brain as a flow, we extended the notion of viscosity to traveling brainwaves. Using this, we explored how brainwave viscosity changes in volunteer propofol anaesthesia.