Cookies on this website

We use cookies to ensure that we give you the best experience on our website. If you click 'Accept all cookies' we'll assume that you are happy to receive all cookies and you won't see this message again. If you click 'Reject all non-essential cookies' only necessary cookies providing core functionality such as security, network management, and accessibility will be enabled. Click 'Find out more' for information on how to change your cookie settings.

Accept all cookies Reject all non-essential cookies Find out more

Contact information


sofia.toniolo@ndcn.ox.ac.uk

Sofia Toniolo

MD, MRCP (Neurology), DPhil, FEBN

Senior Research Fellow and Honorary Consultant Neurologist

  • Cognitive Neurologist
  • Fellow of the European Board of Neurology
  • EAN Dementia and Cognitive Disorders Panel member

Digital Precision Metrics and Plasma biomarkers in Alzheimer's Disease

My research aim is to test whether by combining plasma biomarkers with digital precision cognitive metrics it is possible to develop more sensitive measures to detect Alzheimer's Disease (AD) early and track disease progression over time. I am also interested in using these tools to achieve more precise clinical stratification of subjects at risk of developing AD, such as patients with Subjective Cognitive Impairment (SCI) and Mild Cognitive Impairment (MCI). My work combines individual digital behavioural fingerprints, obtained though tablet or computer based assessments, and biological blood-derived markers of AD pathology. I also use neuroimaging to investigate the structural and functional correlates of these digital behavioural metrics in SCI, MCI and AD patients.