MD, MRCP (Neurology), FEBN
Brain Clinical Post Doctorial Fellow
- Fully trained Neurologist
- DPhil student in Clinical Neurosciences
- Fellow of the European Board of Neurology
- EAN Dementia and Cognitive Disorders Panel member
Digital Precision Metrics and Plasma biomarkers in Alzheimer's Disease
My research aim is to test whether by combining plasma biomarkers with digital precision cognitive metrics it is possible to develop more sensitive measures to detect Alzheimer's Disease (AD) early and track disease progression over time. I am also interested in using these tools to achieve more precise clinical stratification of subjects at risk of developing AD, such as patients with Subjective Cognitive Impairment (SCI) and Mild Cognitive Impairment (MCI). My work combines individual digital behavioural fingerprints, obtained though tablet or computer based assessments, and biological blood-derived markers of AD pathology. I also use neuroimaging to investigate the structural and functional correlates of these digital behavioural metrics in SCI, MCI and AD patients.
Effects of COVID-19 on cognition and brain health.
Zhao S. et al, (2023), Trends Cogn Sci
Digital cognitive test performance and relationship to plasma biomarkers in Alzheimer’s disease
Toniolo S. et al, (2023)
Blood-Brain Barrier Dysfunction and Aβ42/40 Ratio Dose-Dependent Modulation with the ApoE Genotype within the ATN Framework.
Toniolo S. et al, (2023), Int J Mol Sci, 24
Editorial: The role of the cerebellum in dementia and neurodegenerative diseases.
Toniolo S. et al, (2023), Front Neurosci, 17
Epilepsy in Older Persons.
Toniolo S. et al, (2022), Neurol Clin, 40, 891 - 905