Miriam Klein-Flugge

BSc Mathematics/Computer Science (2006), MSc Neuroscience (2008), PhD Neuroscience (2013)

Sir Henry Wellcome Fellow

I am a neuroscientist interested in how the human brain enables us to perform complex types of decisions, for example when desired outcomes are only obtained after delay, physical labour, or sequences of actions. I use brain imaging (fMRI, MEG) as well as causal stimulation techniques (TMS) to study these processes in the healthy human brain.

In my PhD, I was particularly interested in the mechanisms by which decision signals reach motor regions to enable implementation of the resulting actions. In my current postdoctoral fellowship, I am continuing my previous lines of research but I am also planning to study which precise aspects of these computations are impaired in disorders involving abnormal decision-making, such as depression.

Please refer to my personal website (link to the left) for more information.

Recent publications

Model-free decision making is prioritized when learning to avoid harming others.
Journal article

Lockwood PL. et al, (2020), Proc Natl Acad Sci U S A, 117, 27719 - 27730
Polarity of uncertainty representation during exploration and exploitation in ventromedial prefrontal cortex.
Journal article

Trudel N. et al, (2020), Nat Hum Behav
Global reward state affects learning and activity in raphe nucleus and anterior insula in monkeys.
Journal article

Wittmann MK. et al, (2020), Nat Commun, 11
Consistent patterns of distractor effects during decision making.
Journal article

Chau BK. et al, (2020), Elife, 9
Entraining corticocortical plasticity changes oscillatory activity in action control and inhibition
Journal article

Sel A. et al, (2020)

More publications