Contact information
matthew.rushworth@psy.ox.ac.uk
Anne-Marie Honeyman-Tafa
anne-marie.honeyman-tafa@psy.ox.ac.uk
Research groups
Websites
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Wellcome Centre for Integrative Neuroimaging
Research Centre
Matthew Rushworth FRS
MA DPhil
Watts Chair and Professor of Cognitive Neuroscience, Head of Department
- Head of Department
- Wellcome Trust Senior Investigator
Neural mechanisms of decision making and action selection
I am interested in how the brain makes decisions. Every day we make multiple choices about the best course of action to take in a variety of situations. My research is aimed at understanding the brain processes that allow us to work out how good the outcome of a choice might be and which allow us to make decisions between multiple choices.
I have a particular focus on the role played by areas of prefrontal and cingulate cortex. We have found that activity in these brain regions changes as a function of our expectations about how good a choice will be and when a decision is made.
When cognitive processes, such as those involved in decision-making, unfold they involve a number of different brain events. I am also interested in looking at the connexions between brain regions and the interactions they mediate during decision-making and attentional selection.
The lab's focus is on understanding how decision-making mechanisms work in the healthy brain. It is important to understand them because decision-making is such a fundamental aspect of our mental life. In addition, however, we think that some of these processes go awry when people suffer from psychological illnesses.
Recent publications
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Causal necessity of human hippocampus for structure-based inference in learning
Preprint
Pan D. et al, (2025)
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Interpretable abstractions of artificial neural networks predict behavior and neural activity during human information gathering
Preprint
D'Ambrogio S. et al, (2025)
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Dorsal raphe nucleus controls motivation-state transitions in monkeys.
Journal article
Priestley L. et al, (2025), Sci Adv, 11
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Interpretable abstractions of artificial neural networks predict behavior and neural activity during human information gathering
Preprint
D'Ambrogio S. et al, (2025)
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Emotions and individual differences shape human foraging under threat
Journal article
Trier HA. et al, (2025), Nature Mental Health
