In 2013, he was awarded a Principal Fellowship by The Wellcome Trust and moved to Oxford where he is a Professorial Fellow at New College. Previously he was Professor of Clinical Neurology at UCL & The National Hospital for Neurology & Neurosurgery, London and Deputy Director of the UCL Institute of Cognitive Neuroscience.
Masud read Physiological Sciences / Medicine (1981-84) at Oxford before completing his PhD here in 1987. He held a Harkness Fellowship and was a postdoctoral fellow at MIT, prior to returning to Oxford to finish his clinical degree. After Neurology training in London, he held a joint appointment as Consultant Neurologist and Wellcome Trust Senior Fellow (2000-12).
- Graham Bull Prize in Clinical Science, Royal College of Physicians London
- Elizabeth Warrington Prize, British Neuropsychological Society.
- Fellow of Academy of Medical Sciences
MA DPhil BMBCh FRCP FMedSci
Professor of Neurology & Cognitive Neurosicence
- Wellcome Trust Principal Fellow
- Professorial Fellow, New College
My research focuses on
- Attention and memory in healthy people
- Memory disorders in neurodegenerative disorders
- Motivation and apathy in healthy people and patient groups
Why are people inattentive or forget things quickly? Why do some people act impulsively while others just can't be bothered?
All these problems occur to some extent in healthy people. But they can be profoundly disabling in patients with neurological conditions - from stroke through to neurodegenerative conditions such as Parkinson's or Alzheimer's disease and vascular dementia.
Currently, there are very limited treatments. Understanding underlying mechanisms is therefore crucial.
We've developed techniques to examine attention, short-term or working memory and decision-making in healthy people and patients with neurological disorders.
We've begun to understand some of the brain mechanisms that are disrupted when people don't pay attention, or forget information rapidly, when they make impulsive decisions or just can't be motivated to act. Some of our research has led to novel treatments.
Our research on fundamental mechanisms underlying attention, working memory and motivated decision-making in healthy people is conducted in our labs at the Dept of Experimental Psychology and the West Wing, John Radcliffe Hospital.
Changing concepts of working memory.
Ma WJ. et al, (2014), Nat Neurosci, 17, 347 - 356
Dynamic shifts of limited working memory resources in human vision.
Bays PM. and Husain M., (2008), Science, 321, 851 - 854
Functional role of the supplementary and pre-supplementary motor areas.
Nachev P. et al, (2008), Nat Rev Neurosci, 9, 856 - 869
Abnormal temporal dynamics of visual attention in spatial neglect patients.
Husain M. et al, (1997), Nature, 385, 154 - 156
Reward sensitivity deficits modulated by dopamine are associated with apathy in Parkinson's disease.
Muhammed K. et al, (2016), Brain, 139, 2706 - 2721
Apathy in Alzheimer's disease
Nobis L. and Husain M., (2018), Current Opinion in Behavioral Sciences, 22, 7 - 13
Randomised, double-blind, placebo-controlled crossover study of single-dose guanfacine in unilateral neglect following stroke.
Dalmaijer ES. et al, (2018), J Neurol Neurosurg Psychiatry, 89, 593 - 598
Dopamine Modulates Option Generation for Behavior.
Ang Y-S. et al, (2018), Curr Biol, 28, 1561 - 1569.e3
Distinct effects of apathy and dopamine on effort-based decision-making in Parkinson's disease.
Le Heron C. et al, (2018), Brain, 141, 1455 - 1469
Effort but not Reward Sensitivity is Altered by Acute Sickness Induced by Experimental Endotoxemia in Humans.
Draper A. et al, (2018), Neuropsychopharmacology, 43, 1107 - 1118