DPhil student in translational neuroscience
The objective of my DPhil is to study how mild acute stress interacts with Catechol-O-methyltransferase (COMT) genotype and COMT inhibition to affect people's performance on working memory and emotional processing. COMT helps control the level of a brain chemical called dopamine. By conducting our tasks in the 3T MRI scanner we allow brain activity, as well as task performance, to be measured. Our results will have clear implications for the understanding of COMT and its roles, and for the therapeutic use of COMT inhibitors.