Contact information
Research groups
Websites
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Translational Neuroimaging Group (TNG)
Research Group
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FMRIB
NDCN Division
Ludovica Griffanti
Postdoctoral Researcher
PhD
I am a postdoctoral researcher at the Wellcome Centre for Integrative Neuroimaging (WIN), FMRIB. My current research focuses on brain MRI analysis in ageing, dementia and neurodegeneration with the aim to detect possible biomarkers especially for the pre-symptomatic phase of the disease.
I am currently involved in the collection, organisation and analysis of the Oxford Parkinson’s Disease Centre (OPDC) Discovery Cohort MRI sub-study. The OPDC aims to identify early changes in Parkinson’s disease patients before physical symptoms become apparent. The detection of the pre-symptomatic phase using biomarkers, including imaging markers, will allow for early diagnosis of the disease and early intervention through the use of potential neuroprotective therapies.
I am a member of the Translational Neuroimaging Group (TNG) and I am passionate about making research translational and applicable in clinical settings. To this aim I am currently involved in projects that aim to harmonise MRI-derived measures across sites/studies.
As a member of the WIN Analysis group I am also involved in the development of methodological approaches for structural MRI (automated lesions segmentation) and resting state fMRI (artefact removal and reproducibility assessments) part of FSL image analysis software package.
I am involved in post-graduate supervision and in teaching, both within the University of Oxford and at the international FSL course.
Key publications
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BIANCA (Brain Intensity AbNormality Classification Algorithm): A new tool for automated segmentation of white matter hyperintensities.
Journal article
Griffanti L. et al, (2016), Neuroimage, 141, 191 - 205
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Hand classification of fMRI ICA noise components.
Journal article
Griffanti L. et al, (2017), Neuroimage, 154, 188 - 205
Recent publications
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Medium-term effects of SARS-CoV-2 infection on multiple vital organs, exercise capacity, cognition, quality of life and mental health, post-hospital discharge.
Journal article
Raman B. et al, (2021), EClinicalMedicine, 31
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Association of trajectories of depressive symptoms with vascular risk, cognitive function and adverse brain outcomes: The Whitehall II MRI sub-study.
Journal article
Demnitz N. et al, (2020), J Psychiatr Res, 131, 85 - 93
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Multimodal brain-age prediction and cardiovascular risk: The Whitehall II MRI sub-study.
Journal article
de Lange A-MG. et al, (2020), Neuroimage, 222
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Cohort profile: the Oxford Parkinson's Disease Centre Discovery Cohort MRI substudy (OPDC-MRI).
Journal article
Griffanti L. et al, (2020), BMJ Open, 10
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Nigrosome 1 imaging in REM sleep behavior disorder and its association with dopaminergic decline.
Journal article
Barber TR. et al, (2020), Ann Clin Transl Neurol, 7, 26 - 35