Kevin Marche
PhD
Postdoctoral Research Associate
Decision making and motor control in adaptive behaviour
My research interests lie in the fields of information processing in the prefrontal cortex, the premotor cortex, and the striatum, with a particular focus on the role of the midbrain dopaminergic system in signal integration in the striatum.
My current projects encompass three main lines of investigation:
- Action selection and motor control
- Reward-guided choice behaviour in an ambiguous environment (social or economic)
- Learning processes associated with changes in action-outcome contingencies
I am using either simultaneous dual-neuron recordings, fMRI tools, or Reinforcement Learning models in behaving macaque monkeys according to project requirement.
I aim to investigate learning-related changes in neuronal activities, with an emphasis on the following aspects:
- Functional organization of the striatum and its connectivity, related to information processing
- Signal processing in Basal Ganglia neuronal microcircuit
- Social and economic values processing in fronto-striatal functional connectivity
- Cortico-striatal functional connectivity during complex decisions
Recent publications
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Beta Oscillations in Monkey Striatum Encode Reward Prediction Error Signals.
Journal article
Basanisi R. et al, (2023), J Neurosci, 43, 3339 - 3352
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Differential functional connectivity underlying asymmetric reward-related activity in human and nonhuman primates.
Journal article
Lopez-Persem A. et al, (2020), Proc Natl Acad Sci U S A, 117, 28452 - 28462
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Accelerating the Evolution of Nonhuman Primate Neuroimaging.
Conference paper
PRIMatE Data Exchange (PRIME-DE) Global Collaboration Workshop and Consortium. Electronic address: michael.milham@childmind.org None. and PRIMatE Data Exchange (PRIME-DE) Global Collaboration Workshop and Consortium None., (2020), Neuron, 105, 600 - 603
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Changes in activity of fast-spiking interneurons of the monkey striatum during reaching at a visual target.
Journal article
Marche K. and Apicella P., (2017), J Neurophysiol, 117, 65 - 78
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Differences between Dorsal and Ventral Striatum in the Sensitivity of Tonically Active Neurons to Rewarding Events.
Journal article
Marche K. et al, (2017), Front Syst Neurosci, 11