Royal Society Dorothy Hodgkin Research Fellow
The goal of my research is to understand how the brain transforms sensory information into something we can see and feel. The current focus of my research is how images from our two eyes are combined to create a 3-dimensional world. Our ability to see in depth arises in the cerebral cortex, where the similarity and differences in retinal images are compared and fused to create a single image. While early research suggested that stereopsis arises in the primary visual cortex, we now know that many regions in the visual hierarchy respond to binocular disparity. One critical objective is to understand to which extent different regions participate in stereopsis and binocular visuo-motor tasks.
My main methods are a combination of human brain imaging and precise measures of perception. Current neuro-imaging methods allow an insight into how neuronal populations respond to visual stimuli, and can also provide a profile of cortical neurochemicals. Recently, I've started working with volunteers with abnormal binocular vision to help us understand how changes in the balance between the two eyes can affect brain responses and brain chemistry.
Memory recall involves a transient break in excitatory-inhibitory balance.
Koolschijn RS. et al, (2021), Elife, 10
GABAergic inhibition in the human visual cortex relates to eye dominance.
Ip IB. et al, (2021), Sci Rep, 11
A mechanism for hippocampal memory recall based on excitatory-inhibitory fluctuations in neocortex
Koolschijn R. et al, (2020)
Investigating the Relationship Between Eye Dominance and Excitatory/Inhibitory Balance in the Human Visual Cortex Using Combined fMRI-MRS at 7 Tesla
Ip IB. et al, (2020), PERCEPTION, 49, 702 - 702
Relating Eye Dominance to Neurochemistry in the Human Visual Cortex Using Ultra High Field 7-Tesla MR Spectroscopy
Ip IB. et al, (2019), 2019 International Conference on 3D Immersion, IC3D 2019 - Proceedings, 2019-January