My research interests are focused on quantitative MRI, investigating how we can utilise modified imaging acquisitions and novel post-processing algorithms to derive quantitative biomarkers of tissue and obtain information about its microstructural (sub-resolution) properties. In Oxford I am continuing work on an ongoing project investigating the impact of amyotrophic lateral sclerosis (ALS) in the human brain, where we are mapping relationships between multi-modal MR image contrast and histology-derived properties within the same tissue. Prior to Oxford, my my PhD focused on MRI phase as a means to investigate the quantitative and microstructural properties of tissue, including quantitative susceptibility mapping (QSM), susceptibility tensor imaging (STI) and frequency difference mapping (FDM).
Preserved extrastriate visual network in a monkey with substantial, naturally occurring damage to primary visual cortex.
Bridge H. et al, (2019), Elife, 8
Frequency difference mapping applied to the corpus callosum at 7T.
Tendler BC. and Bowtell R., (2019), Magn Reson Med, 81, 3017 - 3031
Intact extrastriate visual network without primary visual cortex in a Rhesus macaque with naturally occurring Blindsight
Bridge H. et al, (2018)
Dissecting the pathobiology of altered MRI signal in amyotrophic lateral sclerosis: A post mortem whole brain sampling strategy for the integration of ultra-high-field MRI and quantitative neuropathology.
Pallebage-Gamarallage M. et al, (2018), BMC Neurosci, 19