Functional MRI (fMRI) has great potential for unravelling mechanisms of functional decline in Alzheimer's disease (AD) and Mild Cognitive Impairment (MCI), but task-fMRI studies have produced conflicting results, partly due to failure to account for underlying morphological changes, and to variations in ability to perform the tasks. Resting-fMRI is promising because it does not require a task. We aimed to improve the understanding of how resting-fMRI relates to brain function.
J Neurol Neurosurg Psychiatry
11/2013
84