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Linear registration methods (FLIRT)

 

  • Uses specifically developed robust global optimisation methodology, coupled with a range of single- and multi-modal cost functions, including Mutual Information, Correlation Ratio, Normalised Correlation, and BBR (Boundary-Based Registration)

Nonlinear registration methods (FNIRT)

 

  • Combines a highly efficient Levenberg-Marquardt modification of the Gauss-Newton optimisation method within a b-spline framework, with additional intensity bias-field modelling.