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We report the intersite scan reliability of diffusion tensor imaging (DTI) parameters using identical 3T scanners and acquisition protocols at 2 sites. Voxel-based analysis revealed several regions with significant intersite differences. The intersite reliability of DTI measures showed coefficients of variation below 4% in tract-specific analysis (TSA) and below 6% in atlas-based analysis. Given the excellent reliability of TSA, our results suggest it as a promising and useful tool for multicenter DTI studies.

Original publication




Journal article


Magn Reson Med Sci

Publication Date





227 - 233


Adult, Anisotropy, Brain, Diffusion Magnetic Resonance Imaging, Diffusion Tensor Imaging, Female, Humans, Male, Middle Aged, Reproducibility of Results