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A protocol is described for obtaining functional magnetic resonance images in anesthetized cat brain based on the blood oxygenation level dependent (BOLD) contrast mechanism. A visual stimulus was used, which consisted of a high-contrast drifting grating, whose speed and spatial frequency was optimized for cat area 18 (V2). Experiments were conducted at 4.7 Tesla using a gradient echo EPI sequence with a 29-ms echo time, yielding signal changes of between 0.7% and 2% in area 18.

Type

Journal article

Journal

Magn Reson Med

Publication Date

11/1997

Volume

38

Pages

699 - 705

Keywords

Animals, Cats, Echo-Planar Imaging, Magnetic Resonance Imaging, Oxygen, Visual Cortex