Large-Scale Gradients in Human Cortical Organization.

Huntenburg JM., Bazin P-L., Margulies DS.

Recent advances in mapping cortical areas in the human brain provide a basis for investigating the significance of their spatial arrangement. Here we describe a dominant gradient in cortical features that spans between sensorimotor and transmodal areas. We propose that this gradient constitutes a core organizing axis of the human cerebral cortex, and describe an intrinsic coordinate system on its basis. Studying the cortex with respect to these intrinsic dimensions can inform our understanding of how the spectrum of cortical function emerges from structural constraints.

DOI

10.1016/j.tics.2017.11.002

Type

Journal article

Journal

Trends Cogn Sci

Publication Date

01/2018

Volume

22

Pages

21 - 31

Keywords

cortical organization, functional hierarchy, gradient, intrinsic coordinate system, spatial arrangement, Animals, Brain Mapping, Cerebral Cortex, Humans

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