Random walk does lead somewhere
Ileana Jelescu, University of Lausanne
WIN Seminar WIN Wednesday
Wednesday, 03 May 2023, 12pm to 1pm
Hybrid via Teams and also in the Cowey Room, WIN Annexe
Join via TeamsDeveloping an in vivo microscope for brain structure and function using diffusion MRI
There is currently no microscopy technique that qualifies as in vivo and non-invasive… or is there? It had been a long winding road, but diffusion MRI combined with biophysical modelling may just fill that role. In this talk, we will (i) go through the latest developments and validation steps of relevant models for quantifying white and gray matter microstructure, (ii) cover their recent applications to a range of diseases, highlighting the added value of diffusion-derived microstructure metrics to disentangle pathological events and trajectories, and (iii) take a fresh look at the potential of diffusion functional MRI to detect brain activity, as an alternative to conventional contrasts that rely on neurovascular coupling.